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Voriconazole CAS 137234-62-9

Chemical Name: Voriconazole

CAS No.: 137234-62-9

Molecular Formula: C16H14F3N5O

Molecular Weight: 349.31

Appearance: White or almost white powder

Category:

Description

Voriconazole Details

Chemical Name: Voriconazole

CAS No.: 137234-62-9

Molecular Formula: C16H14F3N5O

Molecular Weight: 349.31

Molecular Structure:Voriconazole CAS 137234-62-9

Appearance: White or almost white powder

Typical Properties

Item Specifications Results
Appearance White or almost white powder Almost white power
Solubility Very slightly soluble in water;freely soluble in acetone and in methylene chloride Conform
Identification A.Infrared Absorption spectrum is identical to that of Voriconazole reference standard Conform
B.Enantiomeric purity Solution should be clear and colorless Conform
Appearance of solution Solution should be clear and colourless Solution is clear and colourless
Water(KF) Not more than 0.4% <0.1%
Sulfated ash Not more than 0.1% <0.1%
Enantiomeric purity Impurity D not more than 0.2% 0.01%
Impurity E Not more than 0.10% 0.02%
Related compounds(HPLC) Impurity A Not more than 0.15% <0.01%
ImpurityB Not more than 0.15% <0.01%
Impurity C Not more than 0.15% <0.01%
Unspecified impurities Not more than0.10% <0.01%
Total impurities Not more than 0.5% 0.03%
Residual solvents(GC) Ethanol Not more than 5000ppm <LOD(LOD=121ppm)
Acetone Not more than 5000ppm <LOD(LOD=15ppm)
Assay (HPLC) 97.5%-102.0% calculated on the anhydrous basis 99.9%
Bacterial endotoxins Less than 0.2IU/mg Conform
Conclusion It conforms to all the requirements of EP9.0

Voriconazole Usage

Voriconazole is a broad-spectrum triazole antifungal drug used primarily to treat progressive, potentially life-threatening infections in immunodeficient patients.

Packaging and Shipping

Packing: Foil bag , Net weight: 1kg per bag

Voriconazole Storage

The warehouse is ventilated and dry at low temperature away from food

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