Genipin Cas 6902-77-8

GENIPIN Details

Chemical Name: GENIPIN

CAS No.: 6902-77-8

Molecular Formula: C11H14O5

Molecular Weight: 226.23

MolecularStructure:

Appearance: White powder

GENIPIN General Information:
Genipin is a white crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, and is derived from the fruits of Gardenia jasminoides Ellis.

GENIPIN Typical Properties

Item	Specification
Purity    （HPLC）	GENIPIN ≥98%
Appearance	White powder
Physical characteristics
Particle-size	NLT100% 80
Weight loss	≤2.0%
Heavy metal
Total metals	≤10.0ppm
Lead	≤1.0ppm
Mercury	≤1.0ppm
Cadmium	≤0.5ppm
Microorganism
Total number of bacteria	≤1000cfu/g
Yeast	≤100cfu/g
Escherichia coli	Not included
Salmonella	Not included
Staphylococcus	Not included

GENIPIN Usage

It is a natural cross-linking agent extracted from the fruits of Gardenia jasminoides  Ellis.  It can prevent lipid peroxidation and the generation of nitric oxide.  It also has anti-inflammatory and anti-angiogenic effects.

In Tattoo Inks

-Natural Coloring: Genipin itself has color and can react with skin proteins to form stable blue or blue – black complexes for coloring. Compared with chemically synthesized pigments, it has good biocompatibility and low sensitization,  reducing the risk of allergic adverse reactions during the tattooing process.

-Durable Color Display: The complex formed by the combination of genipin and skin proteins is stable, making the tattoo color last for a long time and not easy to fade.

In Hair Dyes

-Natural  Dye  Component:  It  can  interact  with  keratin  in  hair to  color the  hair, which  is attractive to consumers who pursue natural, chemical – free hair dye products.

-Gentle Hair Care: Unlike traditional hair dyes containing ammonia and hydrogen peroxide, genipin  causes  less  damage  to  hair.  It  can  maintain the  luster  and  softness  of  hair,  reducing problems such as dryness and breakage.

-Health-care Efficacy: Its antioxidant and anti – inflammatory properties can protect the hair and scalp during hair dyeing, reduce external damage, and promote scalp health.

Genipin has diverse applications in the medical field, mainly as follows:

-Anti-inflammation: Inhibits the release of multiple inflammatory mediators, relieves acute and chronic inflammation, applicable to treating inflammatory diseases like arthritis and enteritis.

-Neuroprotection:  Improves  nerve function  by inhibiting  neuronal apoptosis and  reducing oxidative stress damage, showing therapeutic  potential  in Alzheimer’s  and  Parkinson’s  disease research.

-Liver protection: Reduces drug-induced and alcoholic liver injuries. The mechanism involves regulating  liver  metabolic  enzyme  activity  and  suppressing  oxidative  stress  and  inflammation, maintaining normal liver function.

-Cardiovascular protection:  Lowers  blood  lipids,  inhibits  platelet  aggregation  and vascular smooth muscle cell proliferation, used for preventing and treating cardiovascular diseases such as atherosclerosis and coronary heart disease.

Antitumor: Inhibits the proliferation of various tumor cells and induces apoptosis. It exerts antitumor activity by regulating tumor cell signaling pathways and inhibiting tumor angiogenesis, offering new ideas and targets for tumor treatment.

-Tissue engineering and regenerative medicine: As a natural cross-linker, it cross-links with biological   macromolecules    like   collagen    and   chitosan    to   form    3D   scaffolds    with   good biocompatibility and mechanical properties, promoting tissue repair and regeneration.

GENIPIN Package and Storage :

25 kg cardboard drum with an inner PE (polyethylene) bag.

Store at  a  low  temperature  ranging  from  -20°C  to  4°C.  Keep  the  environment  dry  to  prevent moisture. Avoid light exposure and use a sealed package to prevent contact with air.