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Alogliptin Benzoate CAS 850649-62-6

Chemical Name: Alogliptin benzoate

Other Name: Avagliptin benzoate

CAS No.: 850649-62-6

Molecular Fomula: C25H27N5O4

Category:

Description

Alogliptin benzoate Quick Details

Chemical Name: Alogliptin benzoate

Other Name: Avagliptin benzoate

CAS No.: 850649-62-6

Molecular Fomula: C25H27N5O4

Chemical Structure:

Alogliptin benzoate

Molecular weight: 461.52

Appearance: White or off-white crystalline powder, odorless

Assay:≥99.0%

Alogliptin benzoate Typical Properties

Item Specifications
Appearance White or off-white crystalline powder, odorless
Melting Point 181~ 185   ℃ ,    Melting    and decomposition
Specific rotation +13    ~ +18
Identification 1. UV: maximum absorption at the wavelength

of 278+2nm

2. IR: Be consistent with standard

3. The retention time of the main peak of the

solution should be consistent

with the

retention time of the main peak

of the

reference solution.

Water NMT 0.5%
Heavy Metal NMT 20ppm
Residue on ignition NMT 0.2%
Residual solvents Etoh NMT 5000ppm DMFNMT 880ppm DCM NMT 600ppm TOL NMT 890ppm  IPA NMT 5000ppm
Related substances Single impurity NMT 0. 1%
Total impurity NMT 2.0%
Assay NLT 99.0%

Alogliptin benzoate application:

Alogliptin benzoate is a DPP-4 inhibitor that selectively inhibits DPP-4 to reduce the inactivation of GLP-1 in the body, increase the level of GLP-1 in the body, and thus lower blood sugar. When blood sugar drops to normal levels, it will no longer continue to play a hypoglycemic role, so it can effectively reduce the risk of hypoglycemia. In addition, DPP-4 inhibitors can also delay gastric emptying, increase satiety, suppress appetite, and help patients lose weight. Therefore, while this type of drug can effectively lower blood sugar, it can also reduce the risk of hypoglycemia and weight gain, overcoming the obstacles that prevent patients from achieving treatment targets and bringing new hope to diabetes treatment.

Packaging and Shipping

25kg/drum

Alogliptin benzoate Storage

Keep closed and store in a dry and ventilated place

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